In the Sweet 16 playoffs of the 2025 NCAA Finals, No. 2 Michigan State and No. 6 Ole Miss and Marquette will square off.
The game will be played on Friday March 28 at 7:09 pm ET, where the two teams will compete for a spot in the Final Eight. The action will take place at State Farm Arena in Atlanta, GA.
Read more about the game below, including the latest odds, my expert prediction and best betting promos to place your bets with.
Best betting promos for Michigan State vs Ole Miss
Find the best promos from the best sportsbooks for the NCAA Finals. Learn more about betting on the tournament in the NCAA Finals betting and strategy guide.
Michigan State (2) vs Ole Miss (6) preview
No. 2 Michigan State has wins over Bryant (87-62) and New Mexico (71-63) thus far. Next up is No. 6 Ole Miss. Against New Mexico, Michigan State was trailing at halftime, 31-29, but they came roaring back in the second half, outscoring the Lobos 42-32.
Jaden Atkins had 16 points, Tre Holloman had 14, and Frankie Fidler had 10. As a team, Michigan State shot 44.4% from the field and 26.7% from 3-point range.
As for Ole Miss, they’ve beaten No. 11 North Carolina (71-64) and No. 3 Iowa State (91-78). The win over Iowa State was massive, as they held a 40-29 halftime lead. Five players had double-digit points, including Malik Dia, Sean Pedulla, Jaylen Murray, Matthew Murrell, and Jaemyn Brakefield.
The Rebels couldn’t be stopped, shooting 58.2% from the field and 57.9% from beyond the arc. They held Iowa State to 8 of 22 (36.4%) from 3-point range. Iowa State played well, but Ole Miss wasn’t missing many shots.
Michigan State vs Ole Miss odds
Below are the odds for this matchup, courtesy of BetMGM.
- Spread: Ole Miss (+3.5, -110); Michigan State (-3.5, -110).
- Moneyline: Ole Miss (+150); Michigan State (-165).
- Total: Over 143.5 (-110); Under 143.5 (-110)
Michigan State Spartans vs Mississippi Rebels analysis
Ole Miss is a fairly well-balanced team. They score 118.8 points per 100 possessions (24th) and allow 95.5 points per 100 possessions (21st).
As for Michigan State, they also average 118.8 points per 100 possessions but surrender just 90.4 points per 100 possessions (fifth).
Ole Miss had some sensational shooting, but this season, they’re shooting 44.6% from the floor (158th) and 34.8% from 3-point range (122nd).
This is noticeably different than their performance against Iowa State.
Michigan State boasts the best defense against 3-point shots, allowing just 27.8% of them to fall in favor of the opposing team.
Michigan State vs Ole Miss pick
Ole Miss was red-hot against Iowa State, but I don’t see that happening against Michigan State. Michigan State’s offense isn’t exciting overall, but its defense is a thorn in the side of all opponents.
Ole Miss is going to see some regression shooting the ball, and I’m not sure they can score enough to beat or cover against Michigan State.
Michigan State -3.5 (-110) at BetMGM
Michigan State vs Ole Miss Game Info
- Who: Michigan State (2) vs Ole Miss (6)
- Date: Friday, March 28
- Time: 7:09 pm ET
- Location: State Farm Arena in Atlanta, GA
- Where to watch: CBS
About the author
Richard Janvrin
Richard Janvrin brings nearly a decade of experience covering sports, sports betting, and everything iGaming. Richard received his bachelor’s degree in Journalism/English from the University of New Hampshire. Throughout his career, Richard has written for sites like Bleacher Report, Forbes, The Game Day, WSN, Gambling.com, and many more.
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